Untimely Loss of life and Cardiovascular Illness Linked to Excessive Glycemic Index Consuming


September 15, 2021 · 7:00 AM

Naan, a kind of flat bread with a excessive glycemic index

Haven’t we all know this for years? From New England Journal of Medication:

Most information relating to the affiliation between the glycemic index and heart problems come from high-income Western populations, with little data from non-Western international locations with low or center incomes. To fill this hole, information are wanted from a big, geographically various inhabitants.


This evaluation contains 137,851 contributors between the ages of 35 and 70 years dwelling on 5 continents, with a median follow-up of 9.5 years. We used country-specific food-frequency questionnaires to find out dietary consumption and estimated the glycemic index and glycemic load on the premise of the consumption of seven classes of carbohydrate meals. We calculated hazard ratios utilizing multivariable Cox frailty fashions. The first final result was a composite of a significant cardiovascular occasion (cardiovascular loss of life, nonfatal myocardial infarction, stroke, and coronary heart failure) or loss of life from any trigger.


Within the examine inhabitants, 8780 deaths and 8252 main cardiovascular occasions occurred in the course of the follow-up interval. After performing in depth changes evaluating the bottom and highest glycemic-index quintiles, we discovered that a weight loss plan with a excessive glycemic index was related to an elevated danger of a significant cardiovascular occasion or loss of life, each amongst contributors with preexisting heart problems (hazard ratio, 1.51; 95% confidence interval [CI], 1.25 to 1.82) and amongst these with out such illness (hazard ratio, 1.21; 95% CI, 1.11 to 1.34). Among the many parts of the first final result, a excessive glycemic index was additionally related to an elevated danger of loss of life from cardiovascular causes. The outcomes with respect to glycemic load had been much like the findings relating to the glycemic index among the many contributors with heart problems at baseline, however the affiliation was not vital amongst these with out preexisting heart problems.


On this examine, a weight loss plan with a excessive glycemic index was related to an elevated danger of heart problems and loss of life.

Supply: Glycemic Index, Glycemic Load, and Cardiovascular Illness and Mortality | NEJM

The Superior Mediterranean Food regimen (2nd version) is low glycemic index.

Steve Parker, M.D.

front cover of Conquer Diabetes and Prediabetes


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