Viagra (one model title for generic sildenafil) is used to deal with erectile dysfunction and pulmonary hypertension. I wager that utilization for ED is way extra frequent than for pulmonary hypertension.

From an article printed in Dec 2021 by Nationwide Institutes of Well being:

…the workforce analyzed insurance coverage claims knowledge from greater than 7 million Individuals. They discovered that the individuals (principally males) who took sildenafil had been 69% much less more likely to develop AD [Alzheimer’s Disease] over 6 years than those that didn’t take the drug. This affiliation between sildenafil and AD held after adjusting for intercourse, age, and different ailments and circumstances.

To know how sildenafil would possibly have an effect on AD, the researchers grew neurons from stem cells derived from AD sufferers. Exposing the cells to sildenafil led to elevated development of neurites, which join neurons to one another, and decreased tau phosphorylation, an early biomarker of AD.

Taken collectively, these outcomes present an affiliation between sildenafil use and lowered AD threat. However the researchers emphasize that they haven’t proven that sildenafil prevents or reverses AD.

This stuff often don’t pan out, however one can hope. How typically had been these guys taking viagra? As soon as a month? Twice every week? To deal with erectile dysfunction, sildenafil is often taken as wanted one hour earlier than sexual exercise. A typical dose for pulmonary hypertension is 20 mg by mouth thrice a day, day by day. Would this drug have an effect on dementia in ladies? As they are saying, additional research are wanted.

Steve Parker, M.D.